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Arylboronic acids are important reagents for the construction of carbon-carbon
bonds and carbon-heteroatom bonds. Especially, arylboronic acid esters have the
advantages of high stability, low toxicity, and easy operation, and are widely
used in the synthesis of drugs and active natural products. .In addition, in
biology, material science and medical research, arylboronic acids have been widely
used in carbohydrate sensors, enzyme inhibitors and nucleoside and carbohydrate
transport carriers. Therefore, the development of efficient and mild aromatic The
synthesis method of boronic acid has always been the focus of chemists. The cross
‐coupling of <a href="http://www.allychem.com/arylboronic-acids-and-derivatives/"
target="_self">arylboronic acids and derivatives</a> with DAST‐type reagents
under mild and metal‐free conditions to directly afford sulfinamides in moderate
to good yields. Moreover, sulfonamides were obtained after a simple oxidation
reaction. The reaction mechanism was investigated by 18O‐labeling experiments,
and the synthetic utility was demonstrated by the sulfoxidation of natural
products.
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<p>
Bis(pinacolato)diboron is widely used in the catalytic monoboration and
diboration of carbon–carbon multiple bonds. Although known for over 90 years,
only in the past two decades has the chemistry of <a
href="http://www.allychem.com/diboron/" target="_self">diboron</a> compounds been
extensively explored. Many interesting structural features and reaction patterns
have emerged, and more importantly, these compounds now feature prominently in
both metal-catalyzed and metal-free methodologies for the formation of B–C bonds
and other processes.
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<p>
Organoboric acid is a class of organoboron compounds with the general formula
R-B(OH)2, also known as hydrocarbyl boronic acid. It is a product in which one
hydroxyl group of boronic acid (B(OH)3) is replaced by an organic group.
Organoboronic acid is more stable than its inorganic acid parent (HB(OH)2), but it
can still be hydrolyzed under acidic conditions to generate boronic acid.
Organoboronic acid has important applications in organic synthesis, such as Suzuki
coupling reaction. Due to their versatility as synthetic intermediates in the
preparation of complex molecules, <a href="http://www.allychem.com/other-organic-
boronic-acids-and-derivatives/" target="_self">boronic acids and derivatives</a>
play important roles in organic synthesis and medicinal chemistry.
</p>
<p>
Potassium trifluoroborates are a special class of organoboron reagents that
offer several advantages over the corresponding boronic acids and esters in that
they are moisture- and air-stable, and are remarkably compliant with strong
oxidative conditions. Sodium tetrafluoroborate is an inorganic compound with
formula NaBF4. It is a salt that forms colorless or white water-soluble rhombic
crystals and is soluble in water (108 g/100 mL) but less soluble in organic
solvents. Sodium tetrafluoroborate is used in some fluxes used for brazing and to
produce boron trifluoride. <a href="http://www.allychem.com/potassium-
trifluoroborate-and-tetrafluoroborate/" target="_self">Potassium Trifluoroborate
and Tetrafluoroborate Salts</a> are both a class of compounds with the anion BF4−.
</p>
<p>
<a href="http://www.allychem.com/chiral-compounds/" target="_self">Chiral
compounds</a> refer to the same molecular weight and molecular structure, but the
left and right arrangements are opposite, such as the real object and its
enantiomer in the mirror. Human's left and right hands have the same
structure, and the order from the big to the little finger is also the same, but
the order is different. The left hand is from left to right, and the right hand is
from the opposite, so it is called "chirality". That is, a pair of
molecules. A chiral compound can contain no improper axis of rotation (Sn), which
includes planes of symmetry and inversion center. Chiral molecules are always
dissymmetric (lacking Sn) but not always asymmetric (lacking all symmetry elements
except the trivial identity). Asymmetric molecules are always chiral.
</p>
<p>
Alkylboronic acids such as methylboronic acid and butylboronic acid are highly
active catalysts for the dehydrative amide condensation of α-hydroxycarboxylic
acids. The catalytic activities of these alkylboronic acids are much higher than
those of the previously reported arylboronic acids. Alkenyl and alkyl acids are
substituted boronic acids with carbon-boron bonds, represented by R-B(OH)2. These
Lewis acids are "green" compounds due to their inherent low toxicity and
rapid environmental degradation. We provide high quality alkenyl acids for <a
href="http://www.allychem.com/alkylboronic-acids-and-derivatives/"
target="_self">alkylboronic acid derivative</a> formation and other chemical
synthesis applications.
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